Abstract

Procedural sedation is recommended for endoscopic ultrasonography (EUS) to enhance patient comfort and optimize procedural conditions. This study aimed to evaluate the impact of continuous propofol infusion as the main component of the sedation protocol on anesthesia-related adverse events during EUS. This single-center observational prospective cohort study was conducted in the endoscopy unit of a territorial hospital. Seventy-five patients were enrolled from April 24 to June 24, 2024. The sedation protocol included intravenous administration of midazolam (0.02 mg/kg), propofol (0.5 mg/kg), and ketamine (0.25 mg/kg), followed by continuous propofol infusion for anesthesia maintenance. Standard monitoring, the Bispectral Index (BIS), and non-invasive end-tidal CO2 monitoring were applied. Adverse events were defined as arrhythmias, bradycardia (HR

Key words: Non-operating room anesthesia, endoscopic ultrasonography, procedural sedation, propofol infusion, patient safety, adverse events