Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Original Article

Open Vet J. 2016; 6(1): 6-14


Post-surgical treatment of thyroid carcinoma in dogs with retinoic acid 9 cis improves patient outcome

V. Castillo, P. Pessina, P. Hall, M.F. Cabrera Blatter, D. Miceli, E. Soler Arias, P. Vidal.

Abstract
The objective of the present study was to compare the effects of isotretinoin 9-cis (RA9-cis) as a post-surgery treatment of thyroid carcinoma to a traditional treatment (doxorubicin) and no treatment. Owners who did not want their dogs to receive treatment were placed into the control group A (GA; n=10). The remaining dogs were randomly placed into either group B (GB; n=12) and received doxorubicin at a dose of 30 mg/m2 every three weeks, for six complete cycles or group C (GC; n=15) and treated with RA9-cis at a dose of 2 mg/kg/day for 6 months. The time of the recurrence was significantly shorter in the GA and GB compared to GC (P=0.0007; P=0.0015 respectively), while we did not detect differences between GA and GB. The hazard ratio of recurrence between GA and GB compared to GC were 7.25 and 5.60 times shorter, respectively. We did not detect any differences between the other groups. The risk ratio of recurrence was 2.0 times higher in GA compared to GC and 2.1 times higher in GB compared to GC. The type of carcinoma had an effect on time of survival with follicular carcinomas having an increased mean survival timethan follicular-compact carcinomas (P

Key words: Differentiated follicular carcinoma, Retinoic acid, Thyroid carcinoma, Thyroid tumour



Similar Articles

Efficient production of oligomeric chitin with narrow distributions of degree of polymerization using sonication-assisted phosphoric acid hydrolysis.
Zhang X, Mao Y, Briber RM
Carbohydrate polymers. 2022; 276(): 118736

Overcoming the limitations of COVID-19 diagnostics with nanostructures, nucleic acid engineering, and additive manufacturing.
Li N, Zhao B, Stavins R, Peinetti AS, Chauhan N, Bashir R, Cunningham BT, King WP, Lu Y, Wang X, Valera E
Current opinion in solid state & materials science. 2022; 26(1): 100966

Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid.
Liu W, Luo H, Wei Q, Liu J, Wu J, Zhang Y, Chen L, Ren W, Shao L
Bioactive materials. 2022; 9(): 92-104

Inulin as a functional ingredient and their applications in meat products.
Illippangama AU, Jayasena DD, Jo C, Mudannayake DC
Carbohydrate polymers. 2022; 275(): 118706

Iminoboronate-chitooligosaccharides hydrogels with strong antimicrobial activity for biomedical applications.
Ailincai D, Rosca I, Morariu S, Mititelu-Tartau L, Marin L
Carbohydrate polymers. 2022; 276(): 118727


Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.



ScopeMed Web Sites