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Evaluation of antibacterial activity of Asparagus racemosus in urinary tract infection

Jinish Jose, Denny Devassykutty.




Abstract

Background: Asparagus racemosus (Shatavari) is widely used in Kerala, for the treatment of urinary tract infection (UTI) both by the rural folks and by traditional doctors without any scientific evidence. In this context, we decided to evaluate the antibacterial property of A. racemosus against common organisms causing UTI.

Aims and Objective: To evaluate and compare the antibacterial activity of alcoholic extracts A. racemosus against common organisms causing UTIs against a standard drug.

Materials and Methods: Fresh roots of A. racemosus were obtained from an organic farm and shade dried, and the ethanolic extract was obtained. The antibacterial activity of three different concentrations 100, 200, and 300 μg was studied using disc diffusion method. The standard drug used for comparison is ciprofloxacin 30 μg. Disc diffusion method was used. Quantitative variables will be expressed in mean standard deviation and their confidence interval. The significance of the difference between groups will be tested using ANOVA, and P < 0.05 will be considered as significant.

Results: The ethanolic extract of A. racemosus does not demonstrate any antibacterial activity when compared to the standard drug ciprofloxacin.

Conclusions: No antibacterial activity for A. racemosus against common organisms which cause UTIs.

Key words: Asparagus racemosus; Antibacterial Activity; Urinary Tract Infections






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