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Research Article

JCDR. 2021; 12(5): 2052-2057

Utility of CSF C-Reactive Protein In Differentiating Bacterial Meningitis From Aseptic Meningitis In Children 1month-12 Years of Age: Prospective Comparative Study

Dr. Sushant Kumar, Dr. Vinod Kumar Mishra, Dr. Sanjeev Kumar.


Aim: The Study of CSF C-reactive protein in meningitis to differentiate bacterial
meningitis from aseptic meningitis in children between 1 month and 12 years of age.
Methods: The Prospective comparative study was conducted in the Department of
pediatrics, Vardhman institute of medical sciences, Pawapuri, Nalanda, Bihar, India, for
15 months. 130 children between 1 month to 12 years of age admitted with acute
history of fever and seizure were included in the study. Patients were divided into 3
groups based on clinical and CSF findings. Group 1 (Bacterial meningitis) was defined
by a CSF leukocyte count of 100–10,000/mm 3 with polymorphonuclear neutrophils
(PMNs) of >50%, a CSF glucose level

Key words: CSF, CRP, diagnostic accuracy, Bacterial Meningitis

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