Medical adhesive-related skin injury (MARSI) is a significant concern in ICU settings, contributing to patient discomfort, prolonged hospital stays, and increased healthcare costs. This systematic review aimed to evaluate the prevalence and identify risk factors associated with MARSI among ICU patients. A comprehensive search was conducted across major databases, including PubMed, Scopus, Web of Science, and Google Scholar, to identify observational studies assessing MARSI prevalence and risk factors in ICU patients. Studies in ICU settings with diverse subpopulations and risk factors were included. The Newcastle-Ottawa scale assessed study quality, and MetaXL 5.3 was used for statistical analyses, with pooled prevalence estimated via a ran dom-effects model. Heterogeneity was assessed using Higgins I² and Cochran’s Q tests. Seven studies, each with 100 to 430 ICU patients, met the inclusion criteria. MARSI prevalence ranged from 10.96% to 42%, with a pooled estimate of 21% (95% CI: 13% to 30%). Consistent risk factors included advanced age, skin fragility, pro longed ICU stay, mechanical ventilation, and chronic conditions such as diabetes and cardiovascular disease. Variations in prevalence appeared related to ICU type and diagnostic methods. MARSI is prevalent among ICU patients, underscoring the need for targeted preventive strategies for at-risk populations. Interventions such as routine skin assessments, selective adhesive use, and alternative fixation methods could reduce MARSI risk. Standardized protocols and further research are recommended to improve comparability and patient outcomes in ICU settings.
Key words: Skin injury, medical adhesive, intensive care unit, MARSI, systemic review
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