Home|Journals|Articles by Year|Audio Abstracts

Original Article

AJVS. 2016; 49(2): 170-177

Effect of Desert Camel's Milk and/or Urine on Experimentally Induced Thioacetamide Liver Cirrhosis in Rats

Mohamed M. Zeweil, Ali H. El-Far, Kadry M. Sadek, Usama E. Mahrous, Ahmed S. Ahmed.


The effects of desert camel milk (CM) and desert camel urine (CU) on thioacetamide-induced liver cirrhosis were studied in rats. Therefore one hundred and thirty male rats were allocated into ten groups. The non-cirrhotic control animals were allocated into five groups each consisted of ten rats. The cirrhotic animals were allocated into five groups. Cirrhotic groups were received CM and CU alone or mixed for 12 weeks with an intraperitoneal (IP) thioacetamide (200 mg/kg) injection. Liver damage was assessed by estimation of tissue oxidant malondialdhyde (MDA) and total antioxidant capacity (TAC). Moreover serum levels of total proteins, albumin, globulin and A/G ratio in addition to alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyl transferase (GGT) and alkaline phosphatase (ALP) activities besides serum bilirubin, cholesterol, triacylglycerols, creatinine and urea were determined. Treatment with CM alone or mixed with CU significantly reduced thioacetamide-induced elevation in tissue MDA as well as serum enzymes (ALT, AST, GGT and ALP), total cholesterol (TC), triacylglycerols (TAG), creatinine and urea. This study gives an evidence that the thioacetamide-induced liver cirrhosis in rats can be ameliorated by administration of CM and CU especially in a dose of 2CM: 1CU.

Key words: Hepatoprotective; Liver Cirrhosis; Thioacetamide; Desert camel milk; Desert camel urine.

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Refer & Earn
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.