Home|Journals|Articles by Year Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Article

J Apither. 2016; 1(1): 33-35

Effect of honey on the body weight of glibenclamide treated alloxan induced diabetic rats.

Onyebuchi Obia, Chinomso Ojiugo Ogwa, Sunday Ogbu Ojeka, Austin Azubuike Ajah, Arthur Nwafor Chuemere.

One of the classical features of diabetes mellitus is weight loss which when excessive may be embarrassing to patients. The rising prevalence of the disease in developing countries coupled with its high cost of management is of great concern. The study is aimed at determining the effect of honey on the body weight of of glibenclamide treated alloxan induced diabetic rats. A total of 20 male wistar rats weighing 200 - 250g were obtained and divided into four groups of 5 rats each. Diabetes was induced in the animals by intraperitoneally injecting 100mg/kg of 2% alloxan solution. Each animal was weighed before and after experiment and recorded accordingly. The animals were respectively administered the following; group 1 received distilled water as 5.0ml/kg/day, group 2 received 5.0ml/kg/day of 50% honey, group 3 received 5.0ml/kg/day of 50% honey together with 0.6mg/kg/day of glibenclamide, group 4 received glibenclamide alone (0.6mg/kg/day). The animals were treated for 4weeks. The present study showed that addition of honey to glibenclamide in the treatment of alloxan diabetic rats significantly reduced weight loss associated with glibenclamide treatment alone. This is due to possible honey.induced pancreatic beta cell regeneration.

Key words: Honey, body weight, glibenclamide, diabetic.

Full-text options

Full-text Article

Share this Article

Readers of this article also read the following articles
»Clinical and Para Clinical Information Needs of Infertility Electronic Health Records in Iran: A Delphi Study
»Novobiocine-Sensitive, Coagutase-Negative Staphylococd in Urinary Cultures: Are They Causative Agents or Contaminants?
»Repair of Coarctation of The Aorta, Bicuspid Aortic Valve, Subaortic Membrane and Ascending Aotic Aneurysm in A Single Session
»Haemorheological effect of pentoxifyllin for the treatment of Oral Submucous Fibrosis: a review
»Treatment of severe tetanus in ICU on mechanical ventilation: Case report
»The effects of sildenafil citrate on some biochemical and hematological parameters in alloxan-induced diabetes (Type I) in male albino rats
»Is there a correlation between hand preference and vertebral-subclavian artery diameter and vertebral artery flow volume?
»Lumbar spine radiographs in iow-back pain
»Antioxidant and Immunostimulant Effect of Carica Papaya Linn. Aqueous Extract in Acrylamide Intoxicated Rats
»Internalizing and Externalizing behavioral problems among patients with Borderline Personality Disorder: Mediating role of Adaptive Family Functioning
»Biochemical Studying of Anabaena (Cyanobacteria) On Nile Tilapia

Journal of Environmental and Occupational Science


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.