Abstract

To highlight troponin elevation associated with non-coronary causes during hemolytic crises in patients with sickle cell disease (SCD), examine the impact of these crises on cardiac function, and determine the prevalence of cardiomyopathy and valvular abnormalities during stable periods. This retrospective study included 41 patients with SCD who presented to the emergency department with hemolytic crises between May 18, 2023, and July 30, 2024. Transthoracic echocardiography (TTE) was performed during the emergency visit and repeated at the 1-month outpatient follow-up. TTE assessments included left ventricular ejection fraction (EF), the presence of dilated cardiomyopathy (DCM), valvular pathologies, and cardiac chamber dimensions. DCM was defined as an EF

Key words: Sickle cell disease, cardiovascular complications, troponin, dilated cardiomyopathy