In this study, two experiments were performed to clarify the effect of dietary supplementation of coconut oil (CO) on the growth, immune response, hematological ,biochemical parameters and mortality of uninfected and experimentally infected rabbits with Ornithobacterium rhinotracheale (ORT) and /or mixed infection of ORT + Pasteurella multocida (P. multocida). To achieve this goal, seventy-two New Zealand White male rabbits were used in this study and divided into 3 groups of 24 rabbits each. The first experiment was represented by the first group, which explored the impact of different dietary levels of CO on normal rabbits and subdivided into four subgroups. The first subgroup fed basal diet (Control) and the second, third and fourth subgroups fed a basal diet supplemented with 1 %, 1.5%, and 2% coconut oil, respectively for 4 weeks. The second group represented the second experiment. The second group was subdivided into four subgroups and subjected to a single infection with ORT infection. The first one was kept as infected control subgroup; the second, 3rd, and 4th infected subgroups were treated with 2% coconut oil, Sulpha-trimethoprim and 2% coconut oil plus sulpha-trimethoprim respectively. The third group was similar to the second group but subjected to mixed infection with ORT+ P. multocida infection for 4 weeks. The results revealed that, the 1st experiment represented by the result of the 1st group which revealed a significant increase (P
Key words: Coconut oil ,rabbits, growth, haematology ,biochemical,Ornithobacterium rhinotracheale , Pasteurella multocida
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