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Natl J Med Res. 2016; 6(1): 62-68

Effects of intrathecal Bupivacaine with normal saline versus Bupivacaine with Fentanyl in patients undergoing surgery

Jigna R Shah, Manish Bhatt.

Objective:To know the effects of intrathecal 0.5% Bupivacaine 2.5 cc with 0.5 cc normal saline and 0.5% Bupivacaine 2.5 cc witth 25 ╬╝g fentanyl for various lower abdominal surgeries.
Methods: A comparative study were conducted in 60 (ASA grade I / II) patients. The onset and duration of both sensory and motor blockade was compared using relevant scales i.e. Sensory scale and Bromage Scale. - Intra-operative and post-operative hemodynamic monitoring was done. The complications which occurred were noted and studied. - The duration of analgesia after sensory wear off was compared between the 2 groups using Visual Analogue Scale. - Quality of post-operative analgesia was studied between the groups.
Results: The duration of sensory and motor block as well as duration of effective analgesia was significantly longer in the bupivacaineľfantanyl group as compared with both bupivacaineľnormal saline groups. Conclusion: Addition of intrathecalfantanyl to bupivacaine was more advantageous than bupivacaine with normal saline with special regard to its analgesic properties among surgical patients.

Key words: Bupivacaine, fentanyl, intrathecal

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