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Natl J Community Med. 2014; 5(1): 10-12

Iron Deficiency Anemia in Pregnancy: Intravenous versus Oral Route

Meghana N Mehta, Jitesh M Shah.

"Background: The aim of this pro-spective, randomized, controlled study was to compare the efficacy of intravenous iron sucrose versus oral iron in the treatment of iron deficiency anemia during pregnan-cy.
Methodology: One hundred fifty pregnant women with gestational age less than 34 weeks with iron deficiency anemia were selected. The women in group A received IV iron sucrose. The drug was admin-istered by IV infusion. The women in the group B received ferrous sulphate as oral iron in the dose of two tablets three times a day. Re-peat laboratory estimations were done after six weeks. Results were analyzed by t test and Z- test of preparation using SPSS 15 and Mi-crosoft excel.
Results: Mean gestational age in group A and group B were 26.13 5.15 weeks and 26.27 4.71 weeks, respectively. Mean Hb level was 6.71 0.65 g/dl in group A which was raised to 10.64 0.71 g/dl. Mean Hb level was 6.72 0.67 g/dl in group B which was raised to 10.17 0.54. The target Hb level of 10 g/dl was achieved in 88% cases in group A and in 76% cases in group B (P =0.055).
Conclusion: Intravenous iron su-crose therapy is safe and as effec-tive as oral iron in the treatment of iron deficiency anemia during pregnancy.

Key words: Iron deficiency anemia, iron sucrose complex, anemia in pregnancy, oral iron.

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