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Original Article

J App Pharm Sci. 2016; 6(10): 055-062

Lignosulfonic Acid Based Hydrogel Nanocomposites for Antimicrobial Application

Chandra Sekhar Espenti, K.S.V. Krishna Rao, K. Madhu Sudana Rao.

A simple free radical polymerization technique for the synthesis of cross-linked AAm/LSA hydrogel for production of silver nanoparticles is established in the present study. The formation of crosslinked network was confirmed by FTIR spectroscopy. Nano composites prove a characteristic surface plasmon band around λmax = 425 nm for the subsistence of Ag nanoparticles surrounded by the hydrogel and these gels are found to be stable under ambient conditions. Results attained with SEM, TEM and UV–visible studies designate that more number of Ag nanoparticles with no individual change in morphology is formed within the hydrogel matrix, on increasing the concentration of Ag+ ions. Compared with pure AAm/LSA gel, the SNCHs display supplementary equilibrium swelling and electron transfer resistance, which are reliant on the amount of Ag nanoparticles present in the hydrogel network. The antibacterial activity of SNCHs suspension showed enhancement the activity towards E.coli and Bacillus.

Key words: Lignosulfonicacid, Ag-Nano composites, Anti-microbial activity and hydrogels

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