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Original Article

PAFMJ. 2015; 65(0): S118-S122


COMPARISON OF PROPHYLACTIC EPHEDRINE AND CRYSTALLOID PRELOAD FOR PREVENTION OF SUBARACHNOID BLOCK INDUCED HYPOTENSION

Syed Ali Raza Ali Shah, Syeda Sarah Naqvi, Muhammad Ali Abbas.

Abstract
Objective: Comparison of crystalloid preloading and prophylactic administration of ephedrine for prevention of spinal anesthesia induced hypotension.
Study Design: Randomized clinical trial.
Place and Duration of Study: study was conducted in anesthesia department, CMH Rawalakot; from 15th Sep 2013 to 11th November 2013.
Material and Methods: Fifty patients were selected for this study, and randomly divided in two groups of 25 each, using random numbers table. Patients of group A received crystalloid preloading, while intravenous ephedrine was given to patients of group B.
Results: Mean age of group A was 23.4 7.32, with minimum age of 14, and maximum age of 45 years. Mean age of group B was 25.04 10.47. Hypotension was present in 11 patients (44%) in group A, and 4 patients (16%) in group B. The difference between the two groups was statistically significant (p=0.031).
Conclusion: Intravenous ephedrine given prophylactically to prevent hypotension is more effective than crystalloid preloading

Key words: Colloid, Crystalloid, Ephedrine, Hypotension, Subarachnoid anesthesia.



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