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Evaluation of Androgen Levels in Patients with Acute Coronary Syndrome

Fatma Dilek Dellal, Mutlu Niyazoğlu, Tamer Çeviker, Süheyla Görar, Ertuğrul Taşan.




Abstract

Objectives: To determine plasma levels of free Testosterone (fT) and dehydroepiandrosterone sulphate (DHEA-S) in male patients with acute coronary syndrome.
Methods: We checked the serum fT and DHEA-S levels of 30 healty male subjects and 64 male patients with acute coronary syndrome whose coronary artery diseases were confirmed by coronary angiography.
Results: We observed no difference between two groups on the level of fT while DHEA-S level was significantly lower (p = 0.01). No correlation had existed between lipid parameters and levels of fT and DHEA-S.
Conclusion: More comprehensive studies are needed about whether lower levels of DHEAS in patients are contributed to acute coronary syndrome or are the effect of disease.

Key words: free testosterone, dehydroepiandrosterone sulphate, acute coronary syndrome, coronary artery disease






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