Aim
Coconut water is a natural beverage that is a part of daily diet of many people. This study was designed to explore anti-inflammatory activity of coconut water of different maturation stages (young and mature) with rat paw-edema model of inflammation using plethysmometer.
Methodology
For this study, albino rats were selected and divided into four equal groups (10 rats in each group). Group 1 was set as control and administered distilled water 1 ml orally, group 2 and 3 were treated with young and mature coconut water respectively at 4ml/100g dose orally. Group 4 was treated with standard drug (ibuprofen) at 400mg/70 kg. 0.1 ml of 1% w/v acetic acid was administered in subplantar tissue of rat paw 30 min after oral treatments of groups. Plethysmometer was used to measure rat paw edema.
Results
Results revealed that both coconut waters possess significant anti-inflammatory activity (p
Key words: anti-inflammatory, coconut water, paw-edema, salicylic acid
|
