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Original Article

J App Pharm Sci. 2016; 6(6): 079-082

Triterpenes and Sterols from Hoya diversifolia Blume

Nelson M. Panajon, Fernando B. Aurigue, Chien-Chang Shen, Consolacion Y. Ragasa.


Chemical investigation of the dichloromethane extracts of Hoya diversifolia Blume led to the isolation of β-amyrin cinnamate (1), squalene (2), β-sitosterol (3), a mixture of β-amyrin (4a), α-amyrin (4b) and lupeol (4c) in a 4:2:1 ratio and saturated hydrocarbons from the leaves; and 2, taraxerol (5), lupeol cinnamate (6), and a mixture of 3 and stigmasterol (7) in a 2:1 ratio from the stems. The structures of 1-7 were identified by comparison of their NMR data with those reported in the literature.

Key words: Hoya diversifolia Blume, Apocynaceae, β-amyrin cinnamate, lupeol cinnamate, squalene, β-sitosterol, α-amyrin, β-amyrin, lupeol, taraxerol, stigmasterol

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