Objective: To evaluate the direct comparison of Fine Needle Aspiration Cytology (FNAC) with tru-cut breast biopsy in palpable suspicious breast lesions.
Methodology: This study was conducted in surgical unit Hayatabad Medical Complex, Peshawar, Pakistan from January 2012 to December 2013. All female patients of age above 20 years with clinically palpable lump were included in the study. Both FNAC and tru-cut biopsy were performed simultaneously in the same setting and the results were compared with final histopathology as gold standard.
Results: A total of 65 patients were evaluated. Mean age of the patients was 39.33±13.52 years. The overall sensitivity of FNAC was 94.9% and that of the trucut biopsy 100%. The specificity for malignancy was 88.2% and 93.5% for FNAC and tru-cut biopsy, respectively.
Conclusion: Although FNAC is a useful and rapid method for evaluating any palpable breast lump, tru-cut biopsy was more sensitive and specific. Tru-cut biopsy had potential benefits for histological diagnosis and information about tumor type, grade, receptor status and use of any neo-adjuvant therapy for breast lesion.
Fine needle aspiration cytology (FNAC), tru-cut biopsy, breast lumps.