One of the most important and feared complications of modern orthopaedic surgery is postperative surgical wound infections. Inthis study, we aimed to investigate antimicrobial resistance rates of isolated microorganisms in wound infections after orthopaedic surgery.Methods- Isolated bacteria were identified with conventional methods and automated system (Becton Dickinson Phoenix ID). Antimicrobialsusceptibility of the strains were investigated according to Clinical Laboratory Standards Institute (CLSI) recommendations.Results- Ninety six (37%) microorganisms were isolated from 257 wound specimens. These were- Acinetobacter spp. 24 (25%), P.aeruginosa 19 (20%), S. aureus 15 (16%), E. coli 10 (10%), K. pneumoniae 10 (10%), CNS 8 (8%), P. mirabilis 5 (5%), Enterobacter spp. 4(4%), and Enterococcus spp. 1(1%), respectively. Acinetobacter spp. strains were resistant to imipenem by 92%, to amikacin by 83%, tociprofloxacin by 89%, and to sulbactam-ampicillin (SAM) by 62%. 10% of E. coli and 40% of K. pneumoniae strains were extended tospektrulu beta-lactamase positive. 7% of S. aureus, 50% of CNS strains were methicillin resistant.Conclusions- Considering local epidemiological data in the treatment of surgical wound infection is going to help increasing the chance oftreatment success and reducing resistance rates by providing rational use of antibiotics-
Key words: Antimicrobial Resistance; Microorganism; Orthopedic Surgical Wound İnfections
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