Abstract

Haploidentical hematopoietic stem-cell transplantation is an optional transplant modality for patients without a Human Leukocyte Antigens-matched donor. Still, one-third of patients who might benefit from allogeneic transplantation are able to find a Human Leukocyte Antigens-matched related donor. In need of immediate stem-cell transplantation, haploidentical donor is an important solution for many patients. Previously, haploidentical hematopoietic stem-cell transplantation was characterised by a high rejection rate, graft-versus-host disease, graft failure, and transplant-related mortality, but there have since been significant improvements in some areas. Development of new extensive T-cell depletion methods with megadose stem cell administration have overcome problems of haploidentical hematopoietic stem-cell transplantation. We presented an applied case haploidentical hematopoietic stem-cell transplantation as an experience in Turgut Ozal Medical Center.

Key Words: Haploidentical; Transplantation; Experience.