Objective: It has been demonstrated that neuthrophil/lymphocyte ratio is an independent prognostic factor in many cancers such as bladder tumor and renal tumor. Whether any differences neuthrophil/lymphocyte ratio regarding the pathological stage of testicular tumor was assessed in this study.
Meterial and Methods: 21 patients underwent orchiectomy for testicular mass in our clinic were included to the study. Neuthrophil/lymphocyte ratios of both groups were obtained from preoperative blood count. Patients were divided into two groups as Group 1 and 2, which contain stage 1 and ≥stage 2 diseases, respectively. Neuthrophil/lymphocyte ratios of both groups were compared statistically using the Mann Whitney U test.
Results: Pathologic examination revealed pure seminoma in 10 patients, mixt germ cell tumor in 6 patients, lymphoma in 1 patient, adenomatoid tumor in 1 patient, fibroma in 1 patient, small round cell ca in 1 patient and leydig cell tumor in 1 patient. Pathologic examination revealed benign pathology in 3 patients. There were 9 patients in each group. The mean neuthrophil/lymphocyte ratios for group 1 and 2 were 1.99 (SD: 0.779) and 2.74 (SD: 1.484), respectively. There was no statistically significant difference between both groups regarding the neuthrophil/lymphocyte ratio (p=0.270).
Conclusion: Neuthrophil/lymphocyte ratio could not predict the pathological stage of testicular tumor preoperatively. Larger series and long-term follow-ups are needed to determine of prognostic effect of neuthrophil/lymphocyte ratio on testicular tumor.
Key Words: Testis; Seminoma; NLR; Prognosis.
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