Abstract

 

The HAIR-AN Syndrome affects about 5% of hirsute women and characterized by insulin resistance, elevated insulin levels, acanthosis nigricans(AN) and hyperandrogenism. The patient presented here is a 21 year-old woman who has secondary amenorrhea, hirsutism, and hyperpigmented skin changes. The patient was given oral contraceptive and spironolactone. After nine months, the patient was observed for significant clinical and hormonal improvement. [Journal of Turgut Özal Medical Center 2(2):204-205,1995]

Key Words : Acantosis nigricans, hirsutismus, insulin resistance ,oral contraceptive, spironolactone