imipenem susceptibility in Gram-negative and positive microorganisms
Dr.İ.Halil ÃZEROL*, Dr.Emine SÃNMEZ**, Dr.Hatice ÃZBİLGE*, Bio.Neşe TAŞTEKİN*.
The Jemale upper genital tract. surgical. intraabdomiııal and a wide variety of infeetions are usııally polimierobic and involve both gram-positive and gram-negative aerobic and anaerobic bacteria. The majoritv of Gram-negative microorganisms are Escherichia coh, Klebsiella. Proteus, Enterobacter and Pseudomonas. Among the Gram-positive microorgansims are usııally Staphylococci. The antimierobial actıvity of imipenem cilastatin (İPM ('S) vas tested for a broad speetrum of 438 organisms isolated Jrom the Microbiologv and Clinical Microbiologv Laboratorv of Eaculty of Medıcine. İnÃ¶nÃ¼ l 'nıversity. Turgut Ãzal Medical Ãenter, behveen January 1 and December 30. 1994. Sınety seven point five percent of 2"5 Gram negative aerobes. 98.1% of 163 Gram positive cocci (Staphylococcus aureus). were found to be sensitive to İPM ('S. inety two point eight percent of 14 Pseudomonas aeruginosa isolates were sensitive to this antibiotic. This study also diselosed that this agent 't as much more aetive against Pseudomonas aeruginosa thaıı any other tested aminoglicosides, as amikacin. netilmicin and tobramycin or cephalosporines, as cephalothme. cefuroxime. ceftnaxone and ceftazidime. /.Journal of Turgut Ãzal Medical Ãenter 2(1): 1 ~- 21.1995/
Key Words . Imipenem-cilastatin, polimicrobic infeetion, E.coli, Pseudomonas, Proteus. Klebsiella, Enterobacter. S. aureus