Ultrasound is commonly used to asses growth of the dominant follicle in patients underwent ovulation induction. Accelerated growth has also been found in clomiphene citrate cycles. This study was performed in 48 patients with ovulatory dysfunction. Twenty-four patients received only clomiphene citrate (CC) while the other 24 patients received CC and conjugated estrogen. Based on the levels of serum E2, T, and the diameters of dominant follicle on 14th day, there was significant difference between study and control groups (p< 0.05). We could not explain the reason of increased dominant follicle diameter, but there were the low levels of serum T in these cycles, and may be this could be a responsible reason. However, to have the exact data, the further hormonal investigation including androgens series and the developed imaging techniques should be used in larger studies. [Journal of Turgut Özal Medical Center 1996;3(3):191-194]
Key Words: Clomiphene citrate, ultrasound monitoring, anovulation, conjugated estrogen
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