The incidence of nosocomial infections was determined as 2% for one-year period in the Turgut Özal Medical Center in 1996. The nosocomial infections were mostly seen in the following departments : intensive care unit (10%), general surgery (7.5%), orthopedic (5.5%) and pediatric (3.3%) wards. Surgical wound infections were the most common type of nosocomial infections (49%), followed by the urinary tract (20%), skin (16%), respiratory tract (8%) infections and bacteremia (6%). The most common nosocomial agents were Enterobacteriaceae members (37%), S.aureus (35%) and P.aeruginosa (18%). Coagulase negative Staphylococci (CNS) and Candida spp. were the other pathogens less frequently isolated. Multiple antimicrobial resistance was found to be 64% in pathogen bacteria. CNS, P.aeruginosa and Enterobacteriaceae members showed more resistance than S. aureus strains. There was an important resistance problem in the hospital and the resistance rates of nosocomial pathogens were determined as follows: 72% to penicillins, 63% to combinations of beta-lactam & f-lactam inhibitor, 30% to cephalosporins, 22% to trimethoprime- sulphamethoxazole, 17% to erytromycin, 15% to chloramphenicole, 7% to aminoglycosides and 5% to new fluoroquinolons. [Journal of Turgut Özal Medical Center 1996;3(3):183-190]
KeyWords : Nosocomial infections, microorganisms, multiple resistance
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