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Ann Med Res. 1997; 4(1): 10-13

Investigation of Chlamydia trachomatis infection with two different methods and administration of azithromycin in treatment of the women with pelvic inflamatory disease


Dr. A. Süha Sönmez1, Dr. Emine Sönmez2, Dr. Bengül Durmaz3, Dr. Mehmet Körolu3, Dr. Hatice Özbilge3




In this study, Chlamydia trachomatis was investigated by solid-phase immunassay (SIA) method (Chlamy-Check-1, Vedalab-France) in endocervical specimens of 106 patients with acute or chronic pelvic inflamatory disease (PID) who presented to Obstetrics and Gynaecology clinic of Research Hospital of nönü University. Fifty one of patients had acute and, remaining had chronic PID. Chlamydia antigen was positive in 4 of acute PID group (7.8%) and in 6 of chronic PID group (10.9%). Chlamydia antigen was also positive in the urethral swabs of husbands of 4 C. trachomatis positive women. Fourteen patients with Chlamydia infection recevied 1 gr single -oral dose of azithromycin. Chlamydia antigen was negative in the control specimens taken on the 7th-10h days of treatment except one patient (92.9%). Rapid diagnostic assays for C. trachomatis screening such as Chlamy-Check-1 can be prefered because it is easily to apply and a sensitive test. Single dose-1 gr azythromycin provided eradication of C. trachomatis antigen in 92.9% of patients and their partners who were found C. trachomatis antigen positive. Further studies with doxycycline and erythromycin are needed to be able to offer azythromycin administration safely in PID cases with C. trachomatis antigen positive. As a conclusion, C. trachomatis should be investigated in patients with acute and chronic PID. [Journal of Turgut Özal Medical Center 1997;4(1):10-13]

Key Words: Chlamydial infection, azithromycin, PID

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