Background/Aim: Obesity and cigarette smoking are important public health problems in the world. Both of them have effects in increasing morbidity and mortality. It has been shown that cigarette smoking decreases insulin sensitivity and increases fat accumulation in the abdominal region. The aim of our study was to compare the obesity parameters like body mass index, waist circumference, blood pressure, glycemic and lipid parameters in smoking and non-smoking morbidly obese women and evaluate the effect of smoking on these parameters retrospectively.
Material and Methods: Eighty three female patients with a body mass index of ? 40 kg/m2 and without an accompanying illness that might lead to endogenous obesity were included in the study. Data was evaluated by dividing patients into two groups as smokers and non-smokers.
Results: There was no statisticaly significant difference among the groups concerning mean age, body mass index, waist circumference, systolic and diastolic blood pressures, fasting blood glucose, insulin, total cholesterol, high density and low density lipoprotein cholesterol and triglyceride levels. Homeostasis Model Assessment of Insulin Resistance was found to be statistically significantly higher in smokers.
Conclusion: In our study, we demonstrated that cigarette smoking increased insulin resistance. To more clearly put forward the effect of smoking on obesity, insulin resistance and related diseases, controlled prospective studies in similar patient populations are required.
Key Words: Morbid obesity, Smoking, Waist circumference, Insulin resistance.