Objective : Elevated level of serum homocystein is accepted as a risk factor which is indefinite, changeable and independent for ischemic strokes. However such a relationship in the hemorrhagic strokes has not been vastly discussed. The goal of this study is to investigate whether the elevated serum homocystein level, as a risk factor for the acute ischemic and acute hemorrhagic strokes, shows a meaningful difference or not.
Material and Methods : 32 patients who were hospitalized with diagnosis of acute ischemic stroke and 32 patients who were hospitalized with diagnosis of acute hemorrhagic stroke in the Neurology Department of Taksim Training and Research Hospital between February 2005 and June 2006 were included in the study group. None of these patients belonging to the two groups defined a stroke history.
The results were evaluated by using the following statistical methods; Mann Whitney U, One-way Variance Analysis, Q square test, Pearson Correlation Analysis, Dunn’s Multiple Comparison Test.
Results : The average of serum homocystein level in ischemic stroke group and in hemorrhagic stroke group were 15,9 +/- 5.4 μmol/l, 15,8 +/- 6.1 μmol/l respectively (normal adult serum homocystein level is 5-14 μmol/l). No meaningful difference with respect to homocystein level found between two groups. (P>0.05)
Conclusion : This study supported that there is no meaningful difference with respect to the elevation of homocystein level between the studied two-groups.
Key Words: Homocysteine, Acute ischemic cerebrovascular disease, Acute hemorrhagic cerebrovascular disease
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