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Ann Med Res. 2009; 16(2): 117-119

Adult Onset Subacute Sclerosing Panencephalitis Beginning with Focal Motor Seizure: Case Report

Özden Kamışlı*, Suat Kamışlı*, Yüksel Kablan*, Şeyda Çankaya*, Cemal Özcan*.


Subacute sclerosing panencephalitis (SSPE) is a slow viral infection of the central nervous system caused by by the measles (rubeola) virus, usually affecting children and rarely young adults. Patients usually have behavioral changes, myoclonus, dementia, visual disturbances, and pyramidal and extrapyramidal signs. The disease has a gradual progressive course leading to death within 1-3 years. The diagnosis is based upon characteristic clinical manifestations, the presence of characteristic periodic EEG discharges, and demonstration of raised antibody titre against measles in the plasma and cerebrospinal fluid. Treatment for SSPE is still undetermined. We present a case of adult onset SSPE’s clinical and laboratory findings with atypical initial symptoms consisting of focal seizure.

Key Words: Subacute Sclerosing Panencephalitis, Focal Seizure

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