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Original Research

Ann Med Res. 2010; 17(2): 91-96


Efficacy and Safety of Etanercept in Patients with Ankylosing Spondylitis

Gökhan Kalı*, Yüksel Ersoy**, Bekir Durmuş**, Zuhal Altay**, Özlem Baysal**, Yasemin Ersoy

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Abstract


 

Objective: The aim of this study was to evaluate efficacy and safety of etanercept in patients with ankylosing spondylitis (AS).

Material and Methods: 21 patients with AS were evaluated before and after 6 months of etanercept treatment based on the clinical and laboratory parameters. Clinical efficacy was determined using criteria defined by the asessment in AS (ASAS) International Working Group (ASAS-20 ASAS-40, ASAS-5/6, and ASAS partial remission) and BASDAI-50 responses.

Results: There were statistically significant improvements in all clinical and laboratory parameters after the six months of etanercept treatment (p






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