Abstract: Retrospective analysis of histologic subtypes of papillary thyroid carcinoma (PTC).
Material and Method: Histopathology reports at the Department of Pathology, Inönü University, Medical School Malatya, Turkey revealed 33 papillary thyroid carcinoma (PTC) cases in a nine year period.
Results: The demographic findings (23 females, 10 males with an average age of 45) were similar to previous reports but the distribution of the PTC subtypes showed some variation. The number and percentage of the PTC subtypes were as following: encapsulated 8 (24%), tall cell 7(21%), follicular 7 (21%), macrofollicular 5 (15%), oncocytic 3 (9%)
and micro-carcinoma 3 (9%). Though the total number of the cases is not suitable for a statistical analysis incidence of the aggressive variant i.e. tall cell subtype is remarkable when compared to other series published. Lymph node metastasis was detected predominantly in the oncocytic (66.7%) and tall cell (%57.1%) subtypes.
Conclusion: Tall cell and oncocytic PTC must be distinguished in the surgical pathology reports precisely for clinical evaluation due to high frequency of lymph node metastasis.
Key Words: Thyroid Cancer, Histopathology, Papillary Thyroid Carcinoma
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