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Case Report

Ann Med Res. 2009; 16(1): 41-44


Stroma-Rich Variant of Castleman Disease Mimicking Retroperitoneal Malign Tumor: Case Report

Nuray Başsüllü*, İlknur Türkmen*, Abuzer Dirican**, Zerrin Calay***, Mahmut Müslümanoğlu****

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Abstract


Castleman’s Disease is a rare entity which is characterized by the benign proliferation of lymphoid tissue. Generally it is asymptomatic and seen in young adults. Mostly it is located in mediastinum but it can also be seen at neck, axillary, intraabdominal and retroperitoneal locations. Most of the retroperitoneal masses are malignant. Because of difficulty in differentiate benign Castleman’s Disease from malign tumors clinically and radiologically, Castleman’s Disease should be remembered in differential diagnosis of retroperitoneal masses. The stroma rich variant is a new subtype of Castleman’s disease and its morphoimmunophenotypical characteristics make it necessary to be differentiated from spindle cell tumors. A 45 years old woman with stromal rich variant hyaline vascular type of Castleman’s Disease with retroperitoneal location is reported due to its rare presence in this localization and possibility of interference with malignant disease.

Key Words: Castleman’s Disease, Stroma-Rich Hyaline Vascular Type, Retroperitoneal Tumor






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