Home|Journals|Articles by Year|Audio Abstracts
 

Original Research

Ann Med Res. 2011; 18(4): 236-239


The Role of Oxidative Stress in Recurrent Pregnancy Loss

 

Özgür Yiğenoğlu*, Mete Gürol Uğur*, Ebru Öztürk*, Özcan Balat*, Özcan Erel**

.




Abstract


 

Objective: To determine the role of oxidative stress in recurrent pregnancy loss by using using a novel automated method

Material and Method: Thirty first trimester pregnant women with history of recurrent pregnancy loss (RPL) and 30 healthy pregnant women were enrolled in this prospective controlled study. The levels of total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) in maternal serum were measured by using the more recently designated Erel method.

Results: We observed statistically significant increased TOS and OSI levels in patient group (p=0.032, p=0.007 respectively). We also demonstrated statistically significant decreased TAS level in pregnant women who had history of RPL (p=0.013).

Conclusion: Our results support the concept that oksidative stress plays a central role in the etiopathogenesis of RPL. Further studies to evaluate the predictive role of TAS, TOS, OSI level by using Erel method are needed.

Key Words: Recurrent Pregnancy Loss, Oxidative Stress.






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.