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Mini Review



Can propolis and caffeic acid phenethyl ester (CAPE) be promising agents against cyclophosphamide toxicity?

Sumeyya Akyol, Mehmet Akif Gulec, Haci Kemal Erdemli, Omer Akyol.




Abstract

Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide has been used to treat a broad of malignancies including Hodgkin’s and non-Hodgking’s lymphoma, Burkitt’s lymphoma, chronic lymphocytic leukemia, Ewing’s sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against cyclophosphamide-induced injuries.

Key words: Propolis; CAPE; cyclophosphamide






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