Home|Journals|Articles by Year|Audio Abstracts RSS - TOC

Chemical properties of Monodora myristica and its protective potentials against free radicals in vitro

Ochuko L. Erukainure, Oluwatoyin V. Oke, Folashade O. Owolabi, Funmi O. Kayode, Emmanuel E. Umanhonlen, Muhammad Aliyu.


Distortion of the balance between the production of reactive oxygen species and the body’s antioxidant defenses against them produces oxidative stress, which intensifies tissue damage. Spices have been reported to possess antioxidant properties which protect against ROS. Monodora myristica is among the common spices in Nigeria with reported medicinal properties. Its proximate composition, phytochemical constituents and antioxidant activities were investigated. The proximate composition ranged from 3.06 to 52.42% with nitrogen free extract having the highest value and ash content, lowest. Phytochemical screening of the spice showed the presence of alkaloids, flavonoids, phenols, tannins and saponins. The 1,1-diphenyl-2 picrylhydrazyl (DPPH) scavenging activity ranged from 16.9 to 71.15 mg gallic acid equivalents (GAE)/g. While the reducing power compared to the standard, gallic acid ranging from 0.028 to 0.126 mg GAE/g. Monodora myristica exhibited high antioxidant activities in vitro, signifying the protective potential of the spice against free radicals. The phytochemicals, phenolic and flavonoids in particular may be responsible for these effective antioxidant properties.

Key words: DPPH; Flavonoid; Phenol; Proximate

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.