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Cyto-histopathological and clinico-radiological evaluation of thyroid lesions

Sandhya M Rani, Dhanraj S Reddy, Srinivas K Rao.


Background: Thyroid swellings are commonly encountered in the surgical practice and accurate preoperative evaluation of thyroid disorder becomes mandatory for proper management of the patient and to avoid unnecessary surgery.

Objective: This study designs to evaluate the clinico-radiological, cyto-histopathological findings, and the accuracy of fine needle aspiration cytology (FNAC) procedure in various thyroid lesions.

Materials and Methods: This prospective study comprises total 147 cases with thyroid lesions referred to cytology laboratory, and gland morphology studied by ultrasonography (USG). FNAC, FNC, and cyst fluid methods were used for specimen collection.

Result: USG examination of thyroid lesions is a more accurate and sensitive diagnostic modality to detect thyroid nodularity. The overall sensitivity and specificity in our study was 83% and 96.42%, respectively, and accuracy of the FNAC in comparison with histopathological examination was 93.8%, and 81.64% thyroid FNACs were cytologically benign, and colloid goiter occupies 58.5%.

Conclusion: The procedure has acceptable sensitivity and specificity in a wide range of patients in the experienced hands and hence, can be followed as a preoperative diagnostic modality in the management of patients with thyroid lesions, thus reducing the number of surgeries.

Key words: Thyroid lesions, FNAC, ultrasonography (USG), histopathology

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