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Original Research

RMJ. 2025; 50(1): 11-14


Evaluation of nicotine replacement therapy's cardiovascular effects and antismoking role

Nisar Ahmed, Muddasar Pervaiz, Muhammad Nadeem Nasim, Sardar Shabbir Ahmad, Nadia Zohair, Shiekh Kashif Rahim.



Abstract
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Objective: To evaluate the impact of nicotine gum on cigarette smoking cessation plans and its potential cardiovascular effects.
Methodology: This observational cohort study was conducted from 16th June 2023 to 31st March 2024. The stratified sampling technique was used to select 220 smokers into two groups (yellow & green) considering 10% of participants leaving halfway, of age groups ranging from 18 to 63 years. The yellow group participants were provided placebo gums and the green group participants were provided nicotine gums. Participants were examined clinically including echocardiography during weekly follow-up visits. Data were analyzed on MS Excel sheets.
Result: The demographic data showed that 61% of the participants were males aged 18 to 28 and were of lower socioeconomic status and of urban background. The green group showed smoking cessation, craving gum, hypertension, tachycardia, and ECG abnormalities in 21%, 13%, 9%, 8%, and

Key words: Nicotine, cigarette smoking, public health.





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030405060708091011120102
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