Guiera senegalensis is widely used in West Africa for traditional medicine. In Northern Nigeria, it is used for general wellbeing by women during postpartum recovery period. In this study, we report the effect of extraction solvents viz acetone, chloroform, ethanol, methanol (each at 50% and 75% concentrations) and water on the phenolic antioxidant and antioxidant activity of G. senegalensis. Total Phenolic Content (TPC) and Total Flavonoid Content (TFC) assays were used to determine the phenolic antioxidants. Antioxidant activity was evaluated by measuring scavenging effect on 2,2ꞌ- diphenyl-1-picrylhydrazyl (DPPH) radical, Ferric Reducing Antioxidant Power (FRAP) and Total Antioxidant Capacity (TAC) using phosphomolybdate assay. Results showed that extraction solvents significantly (P
Key words: Antioxidant activity, extraction solvents, Guiera senegalensis and phenolic antioxidants.
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