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Original Article

J Liaquat Uni Med Health Sci. 2012; 11(1): 24-28


Dermatological Manifestations in Chronic Renal Failure Patients on Haemodialysis

Reema Mirza, Zarnaz Wahid, Humera Talat.

Abstract
OBJECTIVES: The study was carried out to evaluate the prevalence of dermatological problems
in patients undergoing haemodialysis and to document the pattern of these skin alterations.
STUDY DESIGN: Prospective, descriptive.
METHOD: The study comprised of a total number of 300 clinically diagnosed cases of chronic
renal failure belonging to either sex being managed by haemodialysis. A detailed dermatological
examination of these patients was carried out. The results were recorded on a preformed
performa.
RESULTS: There were 169 males and 131 females with the age range of 10-80 years. Maximum
duration of dialysis was 9 years and minimum 1 month. Xerosis (90.66%) was the most common
finding. Pruritus was present in (64.66%). Hyperpigmentation esp. diffuse (54%), oral lesions
(69.3%) including xerostomia and gingival friability, nail changes (61.6%), including pale nails,
polished nails and half and half nails and hair changes (56.6%), including dry coarse hair and
loss of hair from scalp, arms and legs were also present. Other findings included haemorrhagic
diathesis (easy bruisibility, bleeding gums and nasal bleeding), purpuric lesions, excoriation
marks, lichenification, AV Shunt complications, cutaneous infections, hypopigmentation, delayed
wound healing, hyperpigmented macules on palms and soles, calcinosis cutis, gynaecomastia,
solar keratosis and kyrles disease.
CONCLUSION: There is a high prevalence of cutaneous changes in patients undergoing haemodialysis.
At least one cutaneous change was found in 96% of patients. Xerosis was the most
common finding followed by pruritus, diffuse hyperpigmentation, xerostomia, easy bruisibility,
pale nails and half and half nails.

Key words: Dermatological Manifestations; Haemodialysis; Renal Failure; Xerosis; Pruritus.



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