Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles

Open Access

Original Article

J Liaquat Uni Med Health Sci. 2013; 12(3): 161-166

Severity of Anemia during Interferon and Ribavirin Therapy in Patients with Chronic Active Hepatitis C Genotype-3 and its Association with Risk Factors

Aftab Ahmed Sheikh, Mona Humaira, Madiha Zaki, Mohammad Adnan Bawani, Sadik Memon.

Hepatitis C is a major public health problem globally. It is one of the commonest cause of
chronic liver disease in Pakistan. The prevalent genotype is “3” in our country. The standard of
care treatment is combination of interferon and ribavirin. This combination has important adverse
effects especially hemolytic anemia.
AIMS & OBJECTIVES: This study has been conducted to determine the frequency of anemia (<
10gm/dl) at 4, 12 and 24 weeks of interferon and ribavirin treatment CAH-C Genotype-3patients
along with assessment of associated risk factors.
PLACE AND DURATION: This study was conducted in department of Gastroenterology & Hepatology,
Isra University Hospital, Hyderabad, Sindh from April 2009 to October 2010.
STUDY DESIGN: Prospective & case series study
MATERIALS AND METHODS: All patients who fulfilled the inclusion and exclusion criteria were
enrolled. The proforma was filled after patients verbal consent, by asking questions .Their BMI
was recorded and other demographic characteristics were also noted .Patients were followed
at 4,8,12,16,20 and 24 week. Their Blood CP was checked and if Hb fall within the range of 10.1
- 11.9 mg/dL then the dose of ribavirin was reduced (200 mg/day reduction) and if Hb was

Key words: Anemia, interferon and ribavirin, chronic hepatitis C.

Similar Articles

Passive social media use and psychological well-being during the COVID-19 pandemic: The role of social comparison and emotion regulation.
Yue Z, Zhang R, Xiao J
Computers in human behavior. 2022; 127(): 107050

Biovalue in Human Brain Banking: Applications and Challenges for Research in Neurodegenerative Diseases.
Vedam-Mai V
Methods in molecular biology (Clifton, N.J.). 2022; 2389(): 209-220

Using the Health Belief Model to examine travelers' willingness to vaccinate and support for vaccination requirements prior to travel.
Suess C, Maddock J, Dogru T, Mody M, Lee S
Tourism management. 2022; 88(): 104405

Exploring the Alzheimer's disease neuroepigenome: recent advances and future trends.
Zhang H, Elefant F
Neural regeneration research. 2022; 17(2): 325-327

Environmental stocks, CEO health risk and COVID-19.
Fernández-Méndez C, Pathan S
Research in international business and finance. 2022; 59(): 101509

Full-text options

Latest Statistics about COVID-19
• pubstat.org

Add your Article(s) to Indexes
• citeindex.org

Covid-19 Trends and Statistics
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.

ScopeMed Web Sites