Home|Journals|Articles by Year|Audio Abstracts
 

Original Research

RMJ. 2012; 37(4): 387-389


Serum lipid profile as an indicator of the severity of liver damage in cirrhotic patients.

Fazle Subhan, Imran Khan, Rizwana Arif, Abidullah Khan, Adnan Khan.




Abstract

Background and Aims: Lipid abnormalities are commonly observed in cirrhosis liver. This study was conducted to determine lipid profile in cirrhotic patients and to assess its relationship with the severity of the disease.
Materials and Methods: In an analytical cross-sectional study, we studied 204 patients with cirrhosis (case) and 50 age- and sex-matched healthy normolipidemic patients (comparison) .A questionnaire containing personal characteristics, etiology of cirrhosis, pathologic criteria of Child Pugh and MELD (model for end–stage liver disease) and lipid profile (low density lipoprotein and high density lipoprotein, total cholesterol and triglyceride) was completed for every patient.
Results: There was a significant decrease in serum triglyceride, total, LDL and HDL cholesterol levels in patients with cirrhosis compared to the comparison group (mean of 84.2vs. 189.8, 140.9vs. 186.6, 82.5vs. 139.2, and 38.7vs. 42.5 mg/dL, respectively; all p

Key words: Lipid profile cirrhosis, MELD score, Child Pugh Score






Full-text options


Share this Article



Online Article Submission
• ejmanager.com
• ojshosting.net







Do you want to use OJS for your journal ?
work with an experienced partner
www.OJSHosting.net

eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.