Abstract

OBJECT: To find out the frequency of H.pylori infection in patients undergoing upper GI endoscopy.
MATERIALS AND METHODS: This study was conducted at surgical unit-I Liaquat University
Hospital and private hospital located at Hyderabad Sindh from June 2010 to July 2011. After
taking written consent those Patients were enrolled who fulfilled the inclusion criteria. Study
was approved by ethical committee. Presence of H.pylori infection was confirmed by histopathological examination of samples taken during upper gastrointestinal endoscopy. Presence or
absence of gastritis was also observed. GIF 140 Olympus gastro-video-scope was used for the
procedure.
RESULTS: 165 patients were enrolled in the study, among them 82 were males and 83 females
with mean age 41.04 ±15.9 and 35.9 ±11.5 years respectively, among males 43(52.43%) were
positive and 39(47.5%) were negative for H.pylori infection, while in females 38(45.78%) were
positive and 45(54.2%) negative for the same. When compared for gender differences there was
slightly higher prevalence in males. Antral Gastritis was common association with H.pylori infection in both genders with higher prevalence in males as compared to females. 5 patients (5%)
were found to have gastric carcinoma without any H.pylori association
CONCLUSION: Helicobacter pylori infection is quite frequently found in association with gastritis in males as well as females with slightly higher prevalence in male.

Key words: Helicobacter pylori (H.pylori), Antral gastritis, upper gastrointestinal Endoscopy (OGD).