OBJECTIVE: To find out the frequency of carcinoma of gall bladder in the cholecystectomy
specimen sent for histopathology.
DESIGN: Retrospective study.
SETTING: Department of surgery, Liaquat University Hospital, Jamshoro & Depart of Pathology,
Liaquat University of Medical & Health sciences Jamshoro.
DURATION: From January 2007 to December 2008.
METHOD: A retrospective histopathological analysis of specimen collected after cholecystectomies during January 2007 to December 2008 along with patients notes, hospital records were
analyzed. In addition demographic details were also collected. Data was entered into SPSS 13
RESULTS: 521 cases that were operated for cholelithiasis, nineteen were found to have carcinoma of gall bladder with incidence of 3.64%. The age ranged from 35 to 70 years, with mean
age of 54 years in females and 55 years in males. Male to female ratio was 1:3.75. Adenocarcinoma (89.47%) was the most common histological variant.
CONCLUSION: We conclude that carcinoma Gallbladder is having a high incidence of 3.64%,
occurring at an early age with female preponderance. Since preoperative clinical examination
and other radiological investigations cannot diagnose it efficiently in asymptomatic cases,
therefore we suggest every gallbladder specimen should be routinely subjected to histopathology for early and curable management.
Key words: Cholecystectomy, Gall, Bladder specimen, Carcinoma frequency.