OBJECTIVE: To evaluate the effect of preoperative short course of oral steroids followed by
postoperative topical nasal steroids sprays on nasal polyp recurrence after classical intranasal
METHODS: Fifty five patients of both genders with symptoms and signs of nasal polyps were
included in this prospective study between January 2010 and December 2012. Their ages
ranged between 20 and 65 years. The patients were divided into two groups. Group I constituted
30 patients treated by classical sinus surgery (simple nasal polypectomy and intra nasal ethmoidectomy) without oral and local steroid therapy. Group II consisted of 25 patients also
treated by intranasal polypectomy but received preoperatively 60mg prednisolone tablets daily
for one week and postoperatively topical nasal steroid spray (Mometasone furoate suspension)
for three months. All patients were followed up for at least one year. Recurrence of nasal polyps
was assessed endoscopically at three, six and twelve months after surgery. Any evidence of
nasal polyp formation of whatever size was considered as recurrence.
RESULTS: Fifty five patients (35 male and 20 female) with sinonasal polyposis were included in
this study. Male to female ratio was 1.75:1. The patients’ age ranged from 20 to 65 years
and median age was 45 years; median age was 43 years. Recurrence rates at three; six and
twelve months after surgery for the first group of patients were 8.33% (2 patients), 25% (6 patients) and 41.6% (10 patients) accordingly, while the recurrence rates for the second group
were 4.1% (1 patient), 8.3% (2 patients) and 12.5% (3 patients) accordingly.
CONCLUSIONS: Preoperative short course of oral steroid followed by postoperative nasal steroid spray show significant reduction in the recurrence rate of nasal polyps after intranasal polypectomy.
Intranasal Polypectomy, nasal polyp, steroids, Recurrance.