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Original Research

Ann Med Res. 2016; 23(1): 49-52


Cerebral Venous Sinus Thrombosis-Related Epileptic Seizures and Their Clinical Features

M Mehmet Tecellioglu, Ozden Kamisli, Yuksel Kablan.




Abstract
Cited by 0 Articles

Aim: Cerebral venous sinus thrombosis (CVST) is a severe neurological disease that may cause disability and death. Its clinical symptoms are varied. Epileptic seizures may manifest as early signs of the disease in 30-40% of patients. We aim to compare patients presenting with seizures with those presenting without seizures in CVST patients.
Materials and Methods: 50 patients diagnosed with cerebral venous sinus thrombosis were included in the study. The demographic characteristics, initial symptoms, etiologic factors, radiological findings and treatment were analyzed retrospectively. Patients with seizures were evaluated with all their clinical features.
Results: There were 10 patients with epileptic seizures (20%). Nine of the patients were females. All nine female patients had pregnancy-associated seizures. Patients with supratentorial lesions seen was greater than the frequency of seizures. All of the seizures were observed as early seizures (within 14 days). 4 patients focal seizures, secondary generalized seizures were observed in 6 patients. 7 patients who have seizures are also have sagittal sinus thrombosis. Transverse sinus structures affected in the second frequency.
Conclusion: Made in previous studies of patients with DVT reported that about half of the early episodes, in our study, this rate was found to be 20%. Patients who had seizures have similar outcomes with patients without seizures.But the attacks early with an effective antiepileptic treatment was considered to be the prevention of deaths and late seizure recurrence.

Key words: Cerebral Venous Sinus Thrombosis; Seizure; Epilepsy.






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