Abstract

Hepatoid adenocarcinomas (HAC) are very rare extrahepatic tumours that have very poor prognosis. The majority of these tumors are recognized by the height in serum AFP. The incidence rate for reported gastric tumours from the Far East is between 1,3% and 15% but there are only case reports available from other regions. There are two types of HAC: well-differentiated papillary/tubular type and medullary type with polygonal cells. AFP, CEA, CK7, and CK20 have effects on survival. HAC is treated in the way traditional gastric adenocarcinomas are treated. Hepatoid adenocarcinoma of the stomach has poor prognosis. It is often metastatic at diagnosis with an average life expectancy of 4,7 months. Here, we present a rare case of a chemotherapy-resistant patient diagnosed with hepatoid adenocarcinoma in our clinic.

Key words: Hepatoid Adenocarcinoma; AFP; HCC.