Abstract

For decades, traditional medicine has long utilized medicinal plants for their potential in developing new treatments. This study specifically focused on examining the anti-diabetic properties of the aqueous extract derived from Nauclea latifolia leave. Standard procedures were used to conduct phytochemical screening of Nauclea latifolia and amylase activity, glucose uptake activity, and glucosidase activity were assessed following a standard protocol. The results reveal the presence of flavonoids, terpenoids, saponins, alkaloids, anthraquinones, and cardiac glycosides, in the extract further supports its potential antidiabetic effects. These natural compounds have been associated with various health benefits, and their presence in N. latifolia adds to their pharmacological value. However, the results of antidiabetic activity, particularly with the extract revealed notable ability to inhibit amylase activity. This suggests that the extract has potential as a treatment or management option for diabetes mellitus. The study emphasizes the significance of exploring natural herbs as viable alternatives in therapeutic approaches.

Key words: In vitro, Anti-diabetic activities, Nauclea latifolia, Medicinal plants, pharmacological value