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Original Article

J App Pharm Sci. 2015; 5(12): 067-073


Controlled Release of Drugs from Cellulosic Wound Bandage Using Silica Microsphere as Drug Encapsulator Module

Ahmed G. Hassabo, Amina L. Mohamed, Ahmed A. Nada, Nabil Y. Abou Zeid.

Abstract
Diclofenac sodium, linoleic acid and ricinoleic acid can be encapsulated into silica microcapsules, with less than 1 m in size, increasing the possibility of the drug to be controlled released from silica microcapsules at pH condition 6.5 (skin pH), so the silica microcapsule has the potency to be used as drugs carrier and control its release behavior.

Key words: Controlled-drug-releasing, silica microparticles, sodium diclofenac, linoleic acid and ricinoleic acid



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