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A Comparative Study of Oral Hamartoma and Choristoma

Ilana Kaplan, Irit Allon, Benjamin Shlomi, Vadim Raiser, Dror M. Allon.


Aim: To compare the clinical and microscopic characteristics of hamartoma and choristoma of the oral mucosa and jaws and discuss the challenges in diagnosis.
Materials and methods: Analysis of patients diagnosed between 2000-2012, and literature review of the same years. A sub-classification into "single tissue" or "mixed- tissue" types was applied for all the diagnoses according to the histopathological description.
Results: 61 new cases of hamartoma or choristoma were retrieved, the majority were hamartoma. The literature analysis yielded 155 cases, of which 44.5% were choristoma.
The majority of hamartoma were mixed. Among these, neurovascular hamartoma was the most prevalent type (36.7%). Of the choristoma, 59.4% were single tissue, with respiratory, gastric and cartilaginous being the most prevalent single tissue types. The tongue was the most frequent location in both groups.
Conclusion: Differentiating choristoma from hamartoma depends to a great extent on the recognition of the normal tissues expected at every individual location.

Key words: hamartoma; choristoma; tongue; oral mucosa; diagnosis

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