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Original Research

RMJ. 2016; 41(1): 77-80


Survival analysis of breast cancer women according to disease stage

Shamsa Kanwal, Misbah Akram, Sweety Iqbal, Tahira Yasmin.




Abstract

Objective: To predict the survival of breast cancer women with respect to stage of the disease in Punjab, Pakistan and evaluate the impact of the factors on the survival of breast cancer women. Methodology: Medical records of the patients treated during 2009 were obtained from Mayo Hospital and INMOL. Date of diagnosis and stage of disease were confirmed. Patients were contacted on telephone and their follow up was completed by the end of 2013. A total of 563 patients were studied. Kaplan Meier method was applied for the survival analysis. Overall median survival and stage specific median survival was calculated.
Results: Majority of the patients were below 50 years of age. Stage III was the commonest. Two hundred and four deaths were recorded and 359 patients were censored. At a follow up 5 years, median survival of 39 months was seen. Stage I and stage II patients had a median survival of 48 and 34 months, respectively, whereas, in stage III and stage IV a median survival of 26 months and 14 months, respectively.
Conclusion: Median survival of breast cancer patients, irrespective of stage was 39 months. Survival data for early breast cancer patients is not very encouraging. Whereas locally advanced and stage 4 patients had a reasonable survival.

Key words: Breast cancer, survival, stage of disease, Kaplan Meier






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