Home|Journals|Articles by Year Follow on Twitter

Directory for Medical Articles
 

Open Access

Original Research



Prevalence and major causative factors of upper aerodigestive tract malignancies

Pradeep Pooja, Chakramakal Joseph Andrews, Gopinatha Menon Arjun, Arayamparambil Rajagopalan Vinayakumar.

Abstract
Background: The upper aerodigestive tract (UADT) malignancies vary with geography. Data on epidemiology of UADT are few in India, especially southern states such as Kerala.

Objective: To estimate the prevalence and major causative factors of UADT malignancies.

Materials and Methods: In this cross-sectional study, 60 patients (54 male and 6 female subjects) who showed proven UADT malignancies were included. Main epidemiological factors such as age, distribution, site, histopathological types, symptoms, and levels of lymph nodes were determined. The clinical and radiological stages of each site at the time of presentation were also assessed and statistically analyzed.

Result: The male to female ratio was 9:1, with peak incidence in 50% cases at the 6069 years age group. Most common symptom at presentation was change in voice with hoarseness (21/60) and neck swellings (18/60) with lymph node metastasis at the time of presentation. The most commonly involved site was glottis (19/60) with T1 presentation (15/19). Oral cavity lesions found in 11 of 60 cases with seven cases in T4 presentation. Hypopharyngeal malignancies were found in eight cases. Other sites found to be involved were oropharynx, nasopharynx, maxillary sinus, and salivary gland with lesser frequency. Fifty-three cases showed addictions such as tobacco smoking, alcoholism, or tobacco chewing.

Conclusion: The distribution of UADT cancers was the highest in the 6069 years age group with male:female ratio of 9:1. Glottic malignancy showed the highest frequency. Smoking and alcoholism were the major causative factors identified. Hence, the need for education and awareness that are aimed at reducing exposure habit forming substances are emphasized. This study showed limitations such as small sample size and short duration, which warranted further multicenter studies for a longer duration.

Key words: Upper aerodigestive tract malignancies, smoking, alcoholism, lymph node, glottis, oropharynx, nasopharynx, maxillary sinus, salivary gland



Similar Articles

Disparities in Genetic Testing for Heritable Solid-Tumor Malignancies.
Dillon J, Ademuyiwa FO, Barrett M, Moss HA, Wignall E, Menendez C, Hughes KS, Plichta JK
Surgical oncology clinics of North America. 2022; 31(1): 109-126

Use of Sonography in Hand/Upper-Extremity Surgery: Innovative Concepts and Techniques.
Schuind FA, Moungondo F, Van Overstraeten L
Hand clinics. 2022; 38(1): xiii-xiv

Effects of electroacupuncture on pain sensation in a rat model of hyperalgesia with nicotine dependence.
Wang SJ, Zhang YP, Candiotti KA
Neural regeneration research. 2022; 17(4): 905-910

MR imaging of Nasal and Paranasal Sinus Malignant Neoplasms.
Ginat DT
Magnetic resonance imaging clinics of North America. 2022; 30(1): 73-80

Tobacco Use Disorder.
Leone FT, Evers-Casey S
The Medical clinics of North America. 2022; 106(1): 99-112


Full-text options


Latest Statistics about COVID-19
• pubstat.org


Add your Article(s) to Indexes
• citeindex.org






Covid-19 Trends and Statistics
ScopeMed.com
CiteIndex.org
CancerLine
FoodsLine
PhytoMedline
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.



ScopeMed Web Sites